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Robert J. Hickey

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#protein folding Open access Sep 2026

Second-Generation AOH1996 Analogues with Enhanced Pharmacological Properties for Targeting PCNA

Second-generation AOH analogues with enhanced pharmacological properties were created through scaffold optimization, and both compounds induced robust G2/M arrest at lower concentrations than the parent molecule and significantly enhanced transcription–replication conflicts in pancreatic cancer cells.

Pouya Haratipour, Maryam Zangi, Long Gu et al. · 0 citations

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