Open access
Aug 2026
Differential control of both cell cycle-regulated and quantitative histone mRNA expression by Drosophila Mute.
Coupling histone gene expression to S phase of the cell cycle is essential for genome duplication and stability. Activation of Cyclin E/Cdk2 at the G1-S transition stimulates high-level expression of histone genes during S phase, but how histone genes are turned off at the end of S phase is not understood. Here we demo...
M. Geisler, J. P. Kemp, Christina A. Hill et al.
· Genes & Development · 0 citations