Nucleic Acid Capture from Human Blood Plasma Uncovers G-Quadruplex Structures
Ultrashort (US) cell-free DNA (cfDNA) is a population of approximately 50-nucleotide single-stranded DNA molecules in human plasma.1–3 Although it holds biological and diagnostic potential, US cfDNA escapes detection by conventional double-stranded library preparation methods.1–3 Independent studies have linked US cfDN...