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Author

Robert A. Keyzers

2 papers indexed here

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Review Open access Sep 2026

Yeast chemical genetics to investigate mechanism of action of Pacific natural products.

Natural products are a major source of bioactive molecules with important applications in medicine, and investigation of species native to the Pacific region has been particularly fruitful, including species used in traditional and Indigenous medicinal practices. Yeast represents a powerful model system for investigati...

Robyn J. Ooi, Hannah F. Robinson, Ruth Pay et al. · 0 citations
Open access Sep 2026

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont.

An unusually complex modular PKS pathway comprising nonelongating ketosynthases (KSs), two internal thioesterases (TEs), and an acetyl coenzyme A ligase that orchestrate O-acetylation/elimination, acetyl-CoA recycling, and configurational proof-reading to facilitate selective Z-double bond incorporation is revealed.

A. Fraley, M. Rust, Moritz Wagner et al. · 0 citations

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