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Rob Patro

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Open access Sep 2026

Gravlax: an annotation-independent molecular evidence archive for single-cell RNA-seq

A cell-by-gene count matrix is the artifact of a single-cell RNA-seq experiment that is most often stored, shared, and reanalyzed. It is the output of a computation whose inputs are the sequenced molecules and a gene annotation, and while the molecules never change, the annotation is revised continually. Once the matri...

Rob Patro · 0 citations
Open access Aug 2026

Scientific computing in the age of agentic AI: an exploratory field report

Overall, it is found that the use of coding agents in scientific computing holds great promise for accelerating scientific research and increasing the reliability of critical systems, but that outstanding concerns remain.

Jeremiah H. Li, Alex Rubinsteyn, Sergey Feldman et al. · 0 citations

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