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Ritsuko Iwanaga

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Open access Aug 2026

Inhibiting CXCR2 Remodels the Tumor Microenvironment and Blunts Tumor Progression and Dissemination of High-Grade Serous Carcinoma

Abstract High-grade serous carcinoma (HGSC) of the ovary, fallopian tube, and peritoneum has an immunosuppressive tumor immune microenvironment (TIME), mediated in part by infiltrating innate immune cells such as macrophages, neutrophils, and myeloid-derived suppressor cells (MDSC). We hypothesize that manipulating the...

Railey G Mikeska, L. E. Feldman, Elizabeth R. Woodruff et al. · 0 citations

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