Open access
Sep 2026
Preclinical Evaluation of Labetalol for Cutaneous Melanoma Drug Repurposing: Cytotoxic Activity in A375 Cells and Mitochondria-Associated Apoptotic Signaling
LB displayed concentration-dependent in vitro cytotoxicity in A375 melanoma cells, whereas HaCaT keratinocytes showed limited changes under the investigated conditions, providing preliminary evidence supporting further investigation of LB within a melanoma-directed drug-repurposing strategy.
Richard Dahma, E. Moacă, I. Predescu et al.
· Medicina · 0 citations