Rezwanul Islam

SHMT2 Regulates T Cell Homeostasis and Mucosal Inflammation Via Metabolic and Lipid Remodeling 2256280

Serine hydroxymethyltransferase 2 (SHMT2) is a mitochondrial enzyme essential for one-carbon metabolism, nucleotide biosynthesis and redox balance supporting cell proliferation and survival. While SHMT2 is required for the effector CD8+T cells expansion following infection, its role in CD4+T cell development, dif...