Open access
Sep 2026
Delineation of molecular subtypes based on pathway activation signatures reveals intrinsic tumor heterogeneity and pan-cancer shared features
Four distinct molecular subtypes are defined based on the pathway activation profiles of pan-cancer, with each subtype displaying unique features in pathway activation, clinical manifestations, treatment response, survival prognosis, immune microenvironment, and drug sensitivity.
Ren Xu, Xiao Xiao, Jing-Lin Yang et al.
· Frontiers in Oncology · 0 citations