Uveitis, a leading cause of blindness, is driven by dysregulated immune responses, particularly autoreactive T cells. Despite advances in understanding its pathogenesis, key regulatory mechanisms remain elusive. Here, we integrate the cleavage under targets and tagmentation (CUT&Tag) and single-cell RNA sequencing (scR...
He Li, Lei Zhu, Zhao-Huai Li et al.· Science Advances· 0 citations
A critical synthesis of the evidence for intravenous chemotherapy and the transformative role of super-selective intra-arterial chemotherapy (IAC) is provided, and essential randomized controlled trials, technical innovations, and optimized drug regimens are described.
Min Zhou, Jie-Ling Tang, Xu-Yang Wen et al.· Progress in retinal and eye...· 0 citations
This review synthesize current advances in lactate signaling and lactylation in the retina, and examines how their dysregulation contributes to neovascularization, inflammation, and neurodegeneration in disorders including diabetic retinopathy, age-related macular degeneration, autoimmune uveitis and glaucoma.
Xiang Gu, Ai Zhuang, Jiayan Fan et al.· Progress in retinal and eye...· 1 citation
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