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Regina A. Casimiro-Núñez

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Sep 2026

Abstract B003: Developing an all-human model of perineural invasion in pancreatic cancer

Perineural invasion (PNI), the infiltration of nerves by tumor cells, is a hallmark of pancreatic ductal adenocarcinoma (PDAC); however, despite being a clinically relevant phenomenon, the mechanisms underlying PNI remain poorly understood. Most currently available in vitro and ex vivo models rely on murine-sourced n...

Regina A. Casimiro-Núñez, Sydney Willey, Harrison L. Hiraki et al. · 0 citations

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