Regan Kuttler

Enhancing Enzyme Activity Via Noncovalent Association with DNA-Functionalized Nanoparticles

Enhancing enzyme performance without protein engineering remains a central challenge in biocatalysis. Here, we report the unusual discovery that nanoparticles densely functionalized with DNA, commonly known as spherical nucleic acids (SNAs), can bind enzymes without chemical conjugation, affinity tags, or engineered re...