Review
Open access
Aug 2026
From Delivery to Design: Site-Specific Genome Engineering for Next-Generation CAR T-Cell Therapy
Overall, site-specific integration provides a framework for linking CAR placement to therapeutic function, but no single locus or integration strategy is universally optimal and clinical evidence remains limited relative to the expanding preclinical landscape.
Hala Aldahshan, Abeer Al-Hubaysh, Dimah K. Alrabiah et al.
· Biomedicines · 0 citations