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Author

Rebaz Abdulazeez Qader

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Oct 2026

Comparative in silico evaluation of steroidal and non-steroidal sulfamates as potential human steroid sulfatase inhibitors.

Steroid sulfatase (STS) is a membrane-bound enzyme and a key therapeutic target for hormone-dependent disorders. This study evaluates four sulfamate-based STS inhibitors Coumate, Irosustat (STX64), STX213, and STX1938 across both the catalytic core (Site 1) and the secondary membrane-gate vestibule (Site 2) of human ST...

Bahez Ahmed Abdalla, A. Amin, A. K. Ali et al. · 0 citations

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