Pavlovian conditioned approach with different reward magnitudes reveals opposing effects of acute and chronic semaglutide treatment
Rationale Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have attracted interest for their effects on motivational processes beyond satiation and weight loss, including motivation for drug rewards. Reward-predictive cues can acquire motivational value and promote food- and drug-seeking, raising the possibility th...