Open access
Sep 2026
A Data-Driven Adaptive Predictive Control Framework for Stabilizing Dissolved Oxygen and pH in Bioreactor Systems Under Temperature Disturbances
Maintaining stable dissolved oxygen (DO) and pH conditions is critical for reliable operation of bioreactor systems used in cell culture and bioprocess manufacturing. However, accurate regulation of DO and pH remains challenging due to nonlinear process dynamics and variations in operating conditions. In particular, te...
Mu-Hang Li, Zhi-Yu Ji, Jian-Hong Liu et al.
· Processes · 0 citations