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Author

Ran He

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Open access Sep 2026

Network-guided multi-omics characterizes stress-associated transcriptional and metabolic alterations in PFOA-exposed HK-2 proximal tubular cells.

Perfluorooctanoic acid (PFOA) is a persistent per- and polyfluoroalkyl substance that undergoes active renal handling, yet the molecular response of proximal tubular cells remains poorly resolved. We integrated network toxicology with matched RNA sequencing and untargeted LC-MS metabolomics in PFOA-exposed HK-2 cells,...

Yi-Wei Shang, Qi-Kai Luo, You-Rou Zhou et al. · 0 citations
Review Open access Aug 2026

Association between the C-reactive protein–triglyceride-glucose index and obstructive sleep apnea risk

Obstructive sleep apnea (OSA) is characterized by intermittent hypoxia, fragmented sleep, and heightened sympathetic activity, drivers of oxidative stress, systemic inflammation, and metabolic dysregulation. The C-reactive protein–triglyceride-glucose index (CTI) has recently emerged as a composite marker of inflammato...

Wang Wen, Ran He, Zi-Han Fang et al. · 0 citations

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