Author

Rajib Saha

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Open access Sep 2026

Accessing Enzyme Kinetic Data and Prediction Methods at Scale

Enzyme kinetic parameters inform metabolic models, yet experimental measurements are sparse. A growing body of work predicts them from protein and substrate features, but software fragmentation hinders adoption, so downstream tools lock into the most accessible method. We present OpenKinetics Predictor (predictor.openk...

Saleh Alwer, Hugues Escoffier, Karim Taha et al. · bioRxiv · 0 citations

Open access Sep 2026

CatRange enables robust prediction of enzyme variant kinetic regimes

Predicting enzyme kinetics directly from sequence remains a central challenge in computational biology, particularly in resolving the effects of mutations at catalytically essential residues. Existing models frequently overlook the functional consequences of such perturbations, defaulting to wild-type predictions eve...

Karuna Anna Sajeevan, A. Osinuga, B. Arunraj et al. · PNAS Nexus · 1 citation

Open access Jul 2026

Performance of the pBHR1 mobilization protein MobV and its role in stable plasmid expression in Rhodopseudomonas palustris CGA009

This study investigates the effects of pBHR1’s native mobilization protein, MobV, on the retention of pBBR1 origin plasmids in R. palustris, and provides design principles for constructing stable, high-performing vectors in non-model gram-negative hosts.

M. Kathol, Quin Barton, Cheryl M. Immethun et al. · Microbiology spectrum · 0 citations