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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Rajesh Kumar

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2 papers indexed here

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Open access Oct 2026

Plasma nucleosome profiling reports on tumor burden and molecular subtypes in small cell lung cancer

BACKGROUND Small-cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis and marked transcriptional heterogeneity that may drive distinct therapeutic vulnerabilities. Clinical translation of molecular subtyping has been limited by restricted access to tumor biopsies, particularly at relapse. METHODS W...

Gavriel Fialkoff, N. Takahashi, Israa Sharkia et al. · 0 citations
Open access Jul 2026

Spindle Assembly Checkpoint Competency Determines Sensitivity to KIF18A Inhibition in Small-Cell Lung Cancer

This study provides the first mechanistic characterization of KIF18A dependency in SCLC, identifying SAC competency as the primary determinant of response and establishes a biologically informed framework for patient stratification and rational combination strategies relevant to ongoing KIF18A inhibitor clinical trials...

Chiori Tabe, Rajesh Kumar, Yue Huang et al. · 0 citations

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