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Author

Raimar Loebenberg

3 papers indexed here

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Open access Oct 2026

Dose Optimization of Cefazolin for Pediatric Patients with Renal Impairment Using Physiologically Based Pharmacokinetic Modeling (PBPK) in GastroPlus

Background/Objectives: Cefazolin is a first-generation cephalosporin antibiotic widely used for the treatment and prophylaxis of bacterial infections in both adult and pediatric populations. It is predominantly eliminated unchanged by the kidneys. Impaired renal function can reduce its clearance and increase systemic e...

Abdelrahman Abdeen, Yousef A. Bin Jardan, Najia Rahim et al. · 0 citations
Open access Aug 2026

Multi-Target Pharmacological Mechanisms of Cannabidiol in Breast, Colorectal, and Lung Cancer: An Integrated Network Pharmacology and Molecular Docking Study

Combining pooled cancer-associated network pharmacology with co-crystallized ligand benchmarking suggests that CBD may exert its biological activity through coordinated modulation of multiple cancer-related signaling pathways rather than a single molecular target.

Marlon C. Mallillin, A. Chattopadhyay, Irish Mhel C. Mitra et al. · 0 citations
Review Sep 2026

Clinical Pharmacokinetics and Disposition of Imrecoxib

Current evidence is limited by small, mainly single-dose studies, predominantly Chinese populations, and the absence of validated exposure-response relationships integrating imrecoxib, M1, and M2, and the absence of validated exposure-response relationships integrating imrecoxib, M1, and M2.

Sheng-Nan Zhao, Charlie Li, Marlon C. Mallillin et al. · 0 citations

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