Author

Rahul Jagadeesan

2 papers indexed here

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Open access Sep 2026

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

ABSTRACT Combined exposure to thermal and antibiotic stresses is ubiquitous. How cells adapt to these concurrent cues at the single‐gene level remains unresolved. Here, we show that in Escherichia coli, both cold and heat shock responses dominate antibiotic stress responses across multiple levels of physiology. Using R...

Rahul Jagadeesan, A. M. Arsh, Vatsala Chauhan et al. · Advancement of science · 0 citations

Open access Sep 2026

Distinct transcription factor network dynamics underlie early and long-term adaptation to rifampicin in Escherichia coli

ABSTRACT When subject to sublethal rifampicin stress, susceptible Escherichia coli cells quickly adapt to increase survival. We investigated whether the transcription factor network contributes to this adaptation. First, a responsive cohort of 709 genes diverged from the control, suggesting strong disturbance. While th...

M. M. Azevedo, A. M. Arsh, Rahul Jagadeesan et al. · mSystems · 0 citations