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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Raghunath Ranga Sudharshan

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Sep 2026

Abstract A107: Multi-Omic Single-cell Sequencing Reveals KMT2D Loss Activates AP-1-Driven Enhancer Reprogramming to Promote Epithelial-to-Mesenchymal Plasticity in Pancreatic Cancer

KMT2D, a histone H3K4 methyltransferase and critical epigenetic regulator, is mutated in approximately 11% of pancreatic ductal adenocarcinoma (PDAC) cases. Prior work from our group demonstrated that KMT2D loss drives epithelial-to-mesenchymal plasticity (EMP) and tumor progression in PDAC; however, the downstre...

Raghunath Ranga Sudharshan, H. Kim, Heizel Acosta et al. · 0 citations

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