The emergence of artemisinin partial resistance (AR) in Plasmodium falciparum, characterized by mutations in the Plasmodium falciparum Kelch 13 (PfK13) gene and delayed parasite clearance, represents a significant threat to malaria control in Africa. While the Ring-Stage Survival Assay (RSA) is the phenotypic gold stan...
Rafael Oliveira, J. Musabyimana, Emmanuel Kabalisa et al.· Malaria Journal· 0 citations
BACKGROUND
Artemisinin derivatives are central to first-line treatment of both uncomplicated and severe Plasmodium falciparum malaria. Emerging artemisinin partial resistance in east Africa threatens to spread across the continent.
METHODS
In two cross-sectional studies conducted across the ten provinces of Zambia in...
M. Mwenda, Rafael Oliveira, B. Mambwe et al.· Lancet. Infectious Diseases...· 0 citations
COBRA-like (COBL) genes encode plant-specific proteins associated with cell-wall organization, cellulose deposition, and developmental processes. Despite their functional relevance in model plants and crops, this gene family remains poorly characterized in Amazonian Malvaceae species. Here, we performed a comparative g...
Rafael Oliveira, João Victor dos Anjos Almeida, Vitor Trinca et al.· bioRxiv· 0 citations
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