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Rachel M. Bailey

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Open access Oct 2026

A minimally modified AAV9 variant (AAV9fyhr) for enhanced CNS gene delivery by intra-CSF administration

Adeno-associated virus (AAV) mediated gene therapies continue to show promise for the treatment of genetic diseases. However, delivery and safety still represent significant prohibitive barriers restricting translation of these delivery modalities to humans. We describe a novel AAV9 variant, “AAV9fyhr” or “FYHR”, ident...

Irvin T. Garza, V. Ramesh, Yu-Hui Hu et al. · 0 citations

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