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Rachel L. Smith

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#protein folding Open access Oct 2026

T88. LARGE-SCALE LYMPHOBLASTOID CELL LINE TRANSCRIPTOMIC PROFILING OF AUTISM RECAPITULATES PROTEIN FOLDING AND MITOCHONDRIAL ALTERATIONS

Background Autism spectrum disorder (ASD) is a common, heritable, polygenic neurodevelopmental disorder, with hundreds of robustly associated risk genes and loci. Transcriptomic profiling of post-mortem cortex has identified characteristic ASD molecular signatures, including upregulation of protein folding pathways and...

Rachel L. Smith, Michael Jeffrey Gandal · 0 citations

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