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Author

Rachel A. Whitmer

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Nov 2026

Role of APOE ɛ4 and ɛ2 With Longitudinal Cognitive Decline Among Those With Exceptional Longevity: The LifeAfter90 Study.

BACKGROUND AND OBJECTIVES APOE ɛ4 is the strongest genetic risk factor for late-onset Alzheimer disease, while ɛ2 is associated with decreased risk. However, it is unclear how these genotypes relate to cognitive decline among those aged older than 90+. We examined associations of ɛ4 and ɛ2 with longitudinal change in 3...

H. Colbeth, A. Posis, Batool Rizvi et al. · 0 citations

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