This study investigates the therapeutic potential of compounds derived from natural products as anti-inflammatory and analgesic agents. It focuses on their ability to modulate the P2X7 receptor, a key protein involved in purinergic signaling that plays a crucial role in the inflammatory response and pain transmission....
Raíssa Mariaan Dos Stos Galvão, Ana Luisa Palhares de Miranda, R. X. Faria· Current Neuropharmacology· 0 citations
The increasing demand for sustainable agricultural practices has intensified the search for biobased alternatives to synthetic agrochemicals. In this context, marine macroalgae, particularly brown algae (Phaeophyceae), represent a largely underexplored reservoir of structurally diverse secondary metabolites with signif...
I. Soares, Yasmim Leandro França Do Nascimento, Evelize Folly das Chagas et al.· Marine Drugs· 0 citations
This study examines a paradoxical epidemiological transition where declining aggregate national prevalence is counterbalanced by the entrenchment of the disease in high-endemicity “pockets” in the Northeast and Southeast Regions, and argues that simply providing medication is not enough to eliminate schistosomiasis.
I. Soares, K. N. F. Gomes, R. X. Faria· Frontiers in Tropical Diseas...· 0 citations
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