In vitro pharmacological profiling of ITE amide bioisosteric aryl hydrocarbon receptor agonist
Previously, we reported ITE-derived bioisostere 2-(1 H -indole-3-carbonyl)-N-methyl thiazole-4-carboxamide (ITE-CONHCH 3 ) as a high-affinity ligand and potent agonist of the aryl hydrocarbon receptor (AhR) with anti-colitis properties. In the current study, we present its initial in vitro pharmacological profi...
Zdeněk Dvořák, Aneta Grycová, R. Vrzal et al.
· Frontiers in Pharmacology · 0 citations