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Author

R. Upthegrove

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Open access Oct 2026

Predicting Depression Risk in Early Intervention in Psychosis Services: A Machine Learning Study Utilising Electronic Health Records and Natural Language Processing.

INTRODUCTION Depression is prevalent in early psychosis and associated with poorer functional outcomes and suicide risk. Early identification of depression risk is critical to inform targeted interventions. This study aimed to develop models to predict depression risk using electronic health records (EHRs) from patient...

Sergio Mena, Dominic Oliver, F. Coutts et al. · 0 citations
Open access Aug 2026

Disentangling white matter correlates of symptom severity and general impairment in early psychosis.

Disentangling general impairment from psychosis-related symptom severity suggests potentially different underlying processes, and developing imaging biomarkers accounting for these processes may guide early detection strategies and targeted interventions.

N. Penzel, K. Cho, J. Seitz-Holland et al. · 0 citations
Open access Sep 2026

Unraveling Suicidal Ideation and Behaviors in a Global Cohort of Individuals at Clinical High-Risk for Psychosis: Multivariable Correlates and Subthreshold Psychotic Symptoms.

SIB in CHR-P individuals reflects a multidimensional clinical profile primarily outside of core psychosis-risk symptoms, and overall subthreshold psychotic symptoms across the SIB spectrum indicate increasing overall subthreshold psychotic symptoms across the SIB spectrum.

S. Damiani, M. Orlandi, U. Provenzani et al. · 0 citations
Apr 2025

Disrupted Hierarchical Functional Brain Organization in Affective and Psychotic Disorders: Insights from Functional Brain Gradients

Disruptions in the hierarchical organization of brain functional networks in patients with psychotic and affective disorders indicate deficits in functional integration across psychiatric diseases, highlighting the role of attentional and sensory networks in disease processes.

J. Kambeitz, Hannah Hacker, L. Hoheisel et al. · 0 citations
Open access Jul 2026

Disrupted hierarchical functional brain organization in affective and psychotic disorders: insights from functional brain gradients

Disruptions in the hierarchical organization of brain functional networks in individuals with psychotic and affective disorders indicate deficits in functional integration across psychiatric diseases, highlighting the role of attentional and sensory networks in disease processes.

Hannah Hacker, L. Hoheisel, M. Buciuman et al. · 0 citations

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