Ischemic stroke and subsequent reperfusion injury are major causes of mortality and long-term neurological disability, driven by complex mechanisms of excitotoxicity, oxidative stress, neuroinflammation, endothelial dysfunction, and blood-brain barrier disruption. Increasing evidence indicates that long non-coding RNA...
Amr A. El-Sehrawy, I. Sapaev, O. Nematov et al.· Clinica chimica acta; intern...· 0 citations
Breast cancer remains a significant clinical challenge, particularly in triple‑negative breast cancer (TNBC), in which therapeutic resistance limits treatment efficacy. Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a promising strategy to overcome resistance in...
S. Mohammad, A. Vasudevan, Samreet Raizal Rodrigues et al.· Asia-Pacific Journal of Clin...· 0 citations
SIRT1–GAPDH signaling represents a post-translational axis linking sirtuin activity directly to glycolytic enzyme function, distinct from SIRT1's traditional transcriptional roles and serving as a viable molecular checkpoint in microglial immunometabolism.
Chou-Yi Hsu, I. Sapaev, O. Nematov et al.· Frontiers in Immunology· 0 citations
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