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Open access Sep 2026

Ultrastructural dynamics of basal bodies during microgamete formation and fertilisation in Plasmodium

Cilia and flagella are microtubule-based organelles found in a wide range of eukaryotic organisms that form cilia and flagella are assembled from basal bodies. In the malaria parasite, eight flagellated microgametes are assembled from 8 basal bodies that form de novo as a single group (not next to a parent basal body)...

Molly Hair, R. Yanase, David J. P. Ferguson et al. · 0 citations
Open access Oct 2026

Plasmodium protein kinase 2 is required for ookinete-to-oocyst transition and parasite transmission

PK2 is required for Plasmodium berghei oocyst development and transmission. PK2 depletion impairs ookinete motility and apical microneme organisation, prevents oocyst formation and subsequent sporozoite production, and alters phosphorylation of proteins associated with cytoskeletal organisation, invasion, and host inte...

Sarah L. Pashley, Molly Hair, C. V. Ukegbu et al. · 0 citations

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