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R. T. Aruleba

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Open access Oct 2026

A Five-Control Specificity Checklist Overturns an Apparent Phytochemical Disruptor of the VDAC1-Hexokinase-I Interface

Hexokinase-I anchors to voltage-dependent anion channel 1 (VDAC1) at a membrane-buried glutamate, E73, and disrupting this contact is an established anticancer objective. The site-directed docking of natural product libraries into such hotspots routinely identifies disruptors, yet these candidates are rarely tested for...

R. T. Aruleba, Ebenezer Esenogho · 0 citations

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