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Open access Sep 2026

Treatment and outcome of chronic disseminated candidiasis in the era of antifungal prophylaxis: a retrospective multicentre cohort of 111 patients

Summary Background Chronic disseminated candidiasis (CDC) is a severe manifestation of invasive candidiasis predominantly affecting patients with haematological malignancies. Treatment recommendations are based on limited observational data, and the impact of widespread antifungal prophylaxis on CDC epidemiology and ou...

I. Reinhold, I. Ramírez-Sánchez, Pao-Yu Chen et al. · 0 citations
Review Open access Sep 2026

Immunotherapy for invasive Candida infections: Translating host-directed strategies into clinical practice.

BACKGROUND Candida infections are a leading cause of invasive fungal disease (IFD), especially among critically ill and immunocompromised patients. Despite available pathogen-directed antifungal therapies, outcomes remain unsatisfactory with high associated morbidity and mortality rates. Increasing recognition of immun...

R. Sprute, Shakti Singh, Heather R. Conti et al. · 0 citations

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