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Author

R. Soberman

2 papers indexed here

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Open access Sep 2026

Single-Cell Analysis of Non-Functioning Gonadotroph Tumors Identifies Lineage Infidelity and Tumor Growth Programs

Novel transcriptomic signatures determining cell type identity in both APG neuroendocrine and NFG tumor cells are identified, elucidate molecular programs driving NFG lineage infidelity and tumor growth, and highlight candidate predictors of patient outcomes and potential targets for therapeutic intervention.

Evan Dennis, G. Kim, Yun-Li Zhou et al. · 0 citations
Jul 2026

Systematic Targeting of Protein Complexes with Molecular COUPLrs

Small molecules that modulate protein complexes have transformed cell biology and oncology, yet few chemical starting points exist to probe protein-protein interactions. To expand this space, we developed molecular COUPLrs, elaborated small molecules flanked by two cysteine-reactive warheads. Using CONNECT, an integrat...

Diane Yang, S. Harry, H. Chong et al. · 0 citations

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