Open access
Sep 2026
Subepithelial myofibroblasts enhance stem cell regeneration after intestinal epithelial damage.
When intestinal stem cells (ISCs) are damaged, other epithelial cells de-differentiate to restore the ISC compartment. Immune, nerve and lymphatic endothelial cells contribute signals that promote this response, but it is unclear whether or how the native mesenchymal niche senses and responds to ISC loss. In homeostasi...
Neil McCarthy, Camila Mendez Jimenez, Guodong Tie et al.
· Development · 0 citations