Review
Open access
Aug 2026
Modern therapeutic approaches in cholangiocarcinoma: A narrative review of key biomarkers and clinical trials
Highlights • Cholangiocarcinoma (CCA) presents a significant clinical challenge with varied subtypes, each requiring tailored treatments.• Early diagnosis of CCA is difficult, leading to poor survival rates, particularly in advanced stages.• Precision medicine is advancing CCA management through targeted therapies based on specific molecular aberrations.• Recent FDA-approved treatments for CCA include therapies targeting HER2, IDH1, FGFR2, and other key biomarkers.
Augusto Almeida, Joao Manzi, Camila Hoff et al.
· Translational Oncology · 0 citations