Molecular Engineering of Aptamers for Glioblastoma Therapy: From Simple Antagonists to AI-Driven Approaches, a Narrative Review
Glioblastoma multiforme (GBM) is an extremely aggressive and lethal brain tumor, characterized by marked molecular heterogeneity, the persistence of glioma stem cells (GSCs), and the limited permeability of the blood–brain barrier (BBB), which collectively hinder therapeutic efficacy. To address these barriers, nucleic...
L. Di Leandro, Martina Colasante, M. Catanesi et al.
· International Journal of Mol... · 0 citations