Human Hsp70 paralogs display selective J-domain interactions tuning proteostasis under stress.
An evolved hierarchy of paralog-specific JDP couplings that dynamically rewires the Hsp70 network from active repair to protection during stress is revealed, revealing an evolved hierarchy of paralog-specific JDP couplings that dynamically rewires the Hsp70 network from active repair to protection during stress.
Roni Suhler, Lars J W van Beurden, Merav D. Shmueli et al.
· Proceedings of the National... · 0 citations