Introduction: Approximately 5–10% of breast and ovarian cancers are hereditary, predominantly associated with pathogenic variants in BRCA1, BRCA2, and TP53. Cascade genetic testing in at-risk relatives is a cost-effective strategy to enable early detection, targeted prevention, and precision oncology. In the Brazilian...
Elisângela de Paula Silveira-Lacerda, Lis de Paula Lacerda, Luiz Henrique Alves Costa et al.· Mastology· 0 citations
Introduction: This study evaluated the survival rate of women with breast cancer in Goiânia over a 27-year period, comparing race and disease extent.
Methods: A retrospective, population-based cohort study of women with breast cancer in Goiânia. Factors associated with disease extent were analyzed using logistic regres...
M. E. Rocha, R. Rahal, L. R. Soares et al.· Mastology· 0 citations
Introduction: Breast cancer is the most common malignancy among women, with 5–10% of cases arising from hereditary predisposition, driven by pathogenic variants in DNA repair genes such as BRCA1/BRCA2, as well as moderate-risk genes, including ATM, CHEK2, TP53, BARD1, and BRIP1. Next-generation sequencing improves vari...
Bruno Eduardo Feitosa Nascimento, I. M. Calassa, Luiz Henrique Alves Costa et al.· Mastology· 0 citations
Introduction: Breast cancer patients undergoing chemotherapy frequently face a high prevalence of anxiety, depression, and cognitive decline ("chemobrain"), compromising treatment adherence and quality of life.
Objective: This integrative review, part of the doctoral research "Effects of Brief Focal Psychotherapy on A...
Márcia Gomes de Morais, R. Rahal, M. Barbosa et al.· Mastology· 0 citations
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