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R. R. P. P. B. de Menezes

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Open access Jul 2026

Evaluation of Chalcone (E)‑3-(4-Fluorophenyl)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-prop-2-en-1-one against Trypanosoma cruzi (Y Strain): In Vitro Assay, In Silico Drug-Target Analysis, and MPO-Based Drug Likeness

The CPN4F molecule demonstrates potent in vitro efficacy against Chagas disease, outperforming BZN in molecular docking studies targeting cruzain and outperforming BZN in molecular docking studies targeting cruzain.

J. Pinto, Francisco Nithael Melo Lucio, L. R. Ribeiro et al. · 0 citations

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