Highlights What are the main findings? Redox regulation is dynamically coordinated with cell-cycle progression through phase-specific changes in H2O2 generation, sensing, buffering, and resolution. MnSOD, peroxiredoxins, Nrf2/HO-1/NQO1, glutathione, glutaredoxins, GPXs, and the thioredoxin system perform complementary...
R. Patwardhan, S. Morjaria, G. Nandi et al.· Cells· 0 citations
Ionizing radiation (IR) induces oxidative stress and lipid peroxidation with ferroptosis contributing to radiation-induced cancer cell death. Peroxiredoxin 6 (PRDX6), a multifunctional enzyme involved in phospholipid repair and redox regulation, has been implicated in ferroptosis regulation, but its role in the radio...
Debojyoti Pal, R. Patwardhan, S. Sandur· Journal of Proteome Research· 0 citations
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