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R. Ossenkoppele

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Open access Aug 2026

Comparison of quantitative digital and semiquantitative assessments of tau pathology in relation to regional in vivo tau PET.

Quantitative digital image analysis has emerged as a powerful tool for assessing neuropathological burden. Although previous studies have compared quantitative digital and semiquantitative pathology measures, their respective relationships with regionally corresponding in vivo tau PET measures remain poorly characteriz...

Cécilia Tremblay, Tove Freiburghaus, Daria Pawlik et al. · 0 citations
Open access Sep 2026

A Harmonized Visual Reading Framework for Tau PET Staging in Alzheimer Disease

Key Points Question Can a harmonized visual reading framework enable reliable, tracer-agnostic staging of tau positron emission tomography (PET) pathology for clinical use? Findings In this multicenter cross-sectional study of 681 participants scanned with multiple tau PET radiotracers, a 5-class harmonized visual read...

E. Ruppert, M. Vermeiren, Marina Scop Medeiros et al. · 0 citations
Open access Jul 2026

Neuropsychological profiles and behavioural correlates in individuals exposed to repetitive head impacts: findings from the NEwTON study

Repetitive head impacts (RHI) are associated with an increased risk of neurodegenerative disease, most notably chronic traumatic encephalopathy (CTE). This study characterized neuropsychological profiles of RHI-exposed individuals compared to unexposed controls. To investigate whether cognitive dysfunction is lin...

S. Kamps, Esmé H. J. Habraken, S. van Amerongen et al. · 0 citations

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