Author

R. Novaes

2 papers indexed here

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Open access Oct 2026

Drug repurposing-inspired design of miconazole-based 1,2,3-triazoles as antichagasic agents.

Drug-repurposing strategies have been widely explored to accelerate the development of new treatments for Chagas disease, leveraging compounds with previously established safety profiles. Among these, azole antifungals have attracted attention due to their inhibitory activity against 14-α-lanosterol demethylase (CYP51)...

Mariana Araújo Marques, Augusto Vieira Pontes Silva, R. C. F. M. Reis et al. · Bioorganic & Medicinal Chemi... · 0 citations

Open access Aug 2026

The double-edged sword effect of galactoglucomannan-rich Norway spruce (Picea abies) byproduct extract in mice with induced colitis.

Galactoglucomannan (GGM) is a hemicellulosic polysaccharide with emerging prebiotic and immunomodulatory properties. Here, we evaluated the protective potential and biological effects of a Norway spruce byproduct extract (NSBE), a forestry-derived fraction rich in GGM and phenolic compounds, in dextran sulfate sodium (...

T. C. Silva, Amanda dos Santos Lima, Fernando Vitor Vieira et al. · International Journal of Bio... · 0 citations