Co-Solvency-Based Solid Dispersion of Ibuprofen Using Tamarind Seed Mucilage: A Sustainable Approach for Solubility and Bioavailability Enhancement
Ibuprofen is tough to dissolve in water and possess a limited bioavailability. To enhance dissolution, and stability, the study explores co-solvency-based solid dispersion method involving the application of tamarind seed mucilage as a natural polymer carrier. Drug:mucilage ratios of 1:0.5, 1:1, and 1:1.5, employing et...