Tobacco smoking has a strong influence on DNA methylation (DNAm), enabling the development of DNAm-based smoking predictors, yet external evaluations of these have remained limited. We aimed to assess six DNAm-based smoking predictors in a large sample of middle-aged and older Australians for (i) their accuracy and rel...
Xiao-Yu Fan, D. L. Li, Allison M. Hodge et al.· International Journal of Can...· 0 citations
Background: Processed meat and unprocessed red meat are considered carcinogenic and ‘probably carcinogenic’ to humans, respectively, but findings for bladder cancer remain inconsistent. Objectives: We assessed associations between processed meat and unprocessed red meat intake and bladder cancer risk using data from th...
Zi-Yu Wang, N. Afshar, Allison M. Hodge et al.· Cancers· 0 citations
Background Parity and breastfeeding reduce lifetime breast cancer (BC) risk, but the postpartum period is associated with transiently increased risk and poor outcomes. The prognostic significance of reproductive timing in women with germline pathogenic susceptibility variants (PVs) remains unclear. We evaluated the ass...
C. V. van Geelen, L. E. Lara Gonzalez, M. Harris et al.· ESMO Open· 0 citations
BACKGROUND
The role of systemic inflammation in postmenopausal breast carcinogenesis remains unclear. Using a case-cohort study within the Melbourne Collaborative Cohort Study, we estimated the effects of circulating inflammatory biomarkers on the risk of postmenopausal oestrogen receptor (ER)-positive breast cancer....
Frances E. M. Albers, C. Swain, S. G. Dashti et al.· British Journal of Cancer· 0 citations
The gut microbiome has been linked to cancer in many cross-sectional studies. These studies compared individuals with and without cancer, but they do not establish causation. Prospective cohort studies, with faecal samples collected before a cancer diagnosis, will be instrumental in assessing the role of the gut microb...
E. Vogtmann, Caroline Y. Um, S. Zouiouich et al.· The Lancet Microbe· 0 citations
Existing BC risk prediction models provided similar risk discrimination across multiple cohorts, although there was overestimation of risk for high-risk individuals, which supports development of a unified risk model for diverse populations that leverages appropriate incidence rates.
K. Brantley, T. Ahearn, E. Norton et al.· medRxiv· 0 citations
There was little evidence of an overall association between alcohol intake and stomach cancer risk, although modest positive associations were observed among never smokers and in Asian cohorts.
H. Jayasekara, Mo-Lin Wang, Yang Peng et al.· JNCI Cancer Spectrum· 0 citations
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