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Author

R. Milne

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Open access Sep 2026

Circulating Inflammatory Markers and Mammographic Density Phenotypes: a Mendelian Randomization Analysis

A comprehensive analysis of 60 CIMs provides limited evidence supporting broad causal effects of circulating inflammatory markers contributing to variation in MD phenotypes, although most instruments demonstrated weak conditional instrument strength after inclusion of BMI.

A. H. Suger, T. Harrison, C. Haas et al. · 0 citations
Open access Aug 2026

Integration of lipidomic and polygenic risk scores within contemporary clinical cardiovascular risk assessment pathways: a multi-cohort development and validation study

This investigation investigated whether selective integration of lipidomic and genomic risk signals into AusCVDRisk improves 5-year CVD prediction and reclassification, with a focus on individuals at intermediate clinical risk.

Aleksandar Dakic, Jing-Qin Wu, Ting-Ting Wang et al. · 0 citations
Meta-analysis Open access Aug 2026

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

A multi-population meta-analysis of genome-wide association studies, including 32,470 individuals with and 1,753,462 without bladder cancer, identifies 70 independent risk loci, of which 43 are novel, and uses experimental approaches to uncover how inherited variation influences this risk in the context of smoking.

L. Prokunina-Olsson, O. Flórez-Vargas, Michael G. Levin et al. · 0 citations

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