Abstract Background It is well-established that mental illness is associated with excess and premature mortality. Consequently, the assessment of physical health should be routine in the evaluation of persons living with mental disorders. Herein, we introduce the development of a global instrument to assess physical he...
R. McIntyre, Á. Barabássy, Z. Dombi et al.· European psychiatry· 0 citations
BACKGROUND
Acute mixed bipolar/major depression is relatively frequent, yet quantitative information about its pharmacological management is relatively scant, warranting network meta-analysis (NMA) of comparative efficacy/response/acceptability of pharmacological interventions accounting for dose effects across differe...
M. Fornaro, C. Di Lorenzo, Nicolas A. Nunez et al.· Journal of Affective Disorde...· 0 citations
Abstract Background Major depressive disorder (MDD) presents with highly variable clinical symptoms and treatment responses. Patient characteristics can impact treatment outcomes, making it essential to evaluate efficacy across subgroups to establish consistency of treatment effects. Lumateperone is an FDA-approved ant...
W. Earley, S. Durgam, C. Chen et al.· International Journal of Neu...· 0 citations
It is indicated that elunetirom and LL- 340001 engage complementary neuroplasticity and mitochondrial biogenesis-related programs in neuronal systems and support further investigation of brain-targeted thyromimetic signaling as a mechanistically differentiated approach for major depressive disorder and bipolar depressi...
Jason R. Harris, Jill Baccei, W. Stratton et al.· bioRxiv· 0 citations
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