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R. Mak

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Aug 2026

MRI-Guided Reduced-Volume RT for Early-Stage Glottic Cancer: A Prospective Phase 1 Trial with Quantification of Laryngeal Motion.

PURPOSE Five to 7 weeks of whole-larynx radiation (RT) is standard for treatment of early-stage glottic cancer. Previous studies evaluated CT-guided hypofractionated/SBRT treatment to a smaller volume. Magnetic resonance-guided radiotherapy (MRgRT) allows real-time motion tracking and gating by continuously imaging the...

J. Leeman, A. Droznin, C. D. Dwyer et al. · 0 citations
Open access Sep 2026

US population-level model of clinical impact of lorlatinib treatment on ALK+ metastatic non-small cell lung cancer outcomes

Aim: Lorlatinib and alectinib are next-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) approved for the treatment of ALK-positive (ALK+) advanced/metastatic non-small cell lung cancer (NSCLC) after demonstrating superior efficacy over crizotinib (first-generation ALK TKI) in the CROWN and...

Adam Kasle, D. Abrahami, David L. Veenstra et al. · 0 citations
Open access Sep 2026

Validating LLM judges for automated oversight of patient communication

LLMs are increasingly used to mediate patient communication, yet scalable evaluation of their safety, accuracy, and communication quality remains an open problem. LLM judges have emerged as automated evaluators, but whether they can holistically replicate human expert judgment is unvalidated. Informed consent for clini...

Zi-Du Xu, Johnathan Zeng, Shuang Zhou et al. · 0 citations

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