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Open access Oct 2026

Nanoparticles improve targeting and efficacy of endocytosis inhibitors

Endocytosis is a critical cellular process exploited by many viruses, including HIV-1 and SARS-CoV-2, for host cell entry. Inhibiting this pathway provides a promising antiviral strategy; however, existing small-molecule inhibitors often suffer from limited solubility, off-target effects, and poor bioavailability. This...

O. Szewczyk-Roszczenko, Piotr Roszczenko, Iwona Misztalewska-Turkowicz et al. · 0 citations
Open access Sep 2026

5-((5-Nitrofuran-2-yl)allylidene)-2-thioxo-4-thiazolidinones Target Microtubules in Breast Cancer Cells

4-Thiazolidinone derivatives, a group of compounds with a broad spectrum of activity and anticancer properties, are used in medicine as anti-inflammatory, antiviral, antibacterial, antidiabetic, and blood pressure-lowering drugs; some of them are now in phase II and III clinical trials as anticancer drugs. Here, we eva...

Magdalena Podolak, Rostyslav Dudchak, Agnieszka Gornowicz et al. · 0 citations

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