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R. Koeppe

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Open access Sep 2026

Are the factors associated with cognitive performance generalizable across cohorts?

Tau pathology in the presence of Aβ was a stronger predictor of cognition in ADNI than in U.S. POINTER, and this discrepancy was not explained by increased vascular risk or brain atrophy in U.S. POINTER.

Pei-Wei Liu, Theresa M. Harrison, H. Snyder et al. · 0 citations
Open access Aug 2026

EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease

Findings support the potential value of EOAD-signature atrophy as an MRI-based biomarker for individualized prognostication and clinical trial stratification and support the potential value of EOAD-signature atrophy as an MRI-based biomarker for individualized prognostication and clinical trial stratification.

T. Paranhos, Yuta Katsumi, M. Brickhouse et al. · 0 citations
Open access Jul 2026

Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

A double-cutoff analysis suggest that scans in the 11 to 26 Centiloid range should be interpreted with caution depending on the context of use, and positivity cutoffs converged around 18 Centiloids (data-driven) and 27 Centiloids (visual reads).

G. Blazhenets, D. Soleimani-Meigooni, Konstantinos Chiotis et al. · 5 citations

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